Capt. Michael Donaldson with the Buchanan County Drug Strike Force said a series of smaller investigations led to the arrests.
Eighteen suspects were arrested on state warrants. Five were arrested on federal warrants.
The arrests came on felony drug warrants, focused on the selling of methamphetamine, marijuana, and prescription drugs.
The Buchanan County Sheriff's Department, the St. Joseph Police Department, and the Drug Enforcement Administration helped in the arrests.
The names of the eighteen suspects arrested on state warrants include: Leo Ballard, Caleb Blackburn, Cary Dennis, Richard Dulan, Gregory Fairchild, Jessica K. Faulkner, Christopher Faulkner, Jerry Grippando, Danell J. Guffey, Amanda Hughes, Tracy L. Keith, Joey Mace, Clay Novak, Bradley Perry, Tracy Roacha, Laura Roacha, Jarem Weldon, Cathy Wells.
The names of the five suspects arrested on federal warrants include: Shannon Martinez, Joshua Jensen, Jimmy Hargrave, Ricky Billings, Shawn Hatfield.